Ontology highlight
ABSTRACT:
SUBMITTER: Das P
PROVIDER: S-EPMC4438666 | biostudies-literature | 2015 May
REPOSITORIES: biostudies-literature
Scientific reports 20150520
Enveloped viruses enter host cells through membrane fusion and the cells in turn alter their shape to accommodate components of the virus. However, the role of nonmuscle myosin II of the actomyosin complex of host cells in membrane fusion is yet to be understood. Herein, we show that both (-) blebbistatin, a specific inhibitor of nonmuscle myosin II (NMII) and small interfering RNA markedly augment fusion of Sendai virus (SeV), with chinese hamster ovary cells and human hepatocarcinoma cells. In ...[more]