Ontology highlight
ABSTRACT:
SUBMITTER: Klein AM
PROVIDER: S-EPMC4441768 | biostudies-literature | 2015 May
REPOSITORIES: biostudies-literature
Klein Allon M AM Mazutis Linas L Akartuna Ilke I Tallapragada Naren N Veres Adrian A Li Victor V Peshkin Leonid L Weitz David A DA Kirschner Marc W MW
Cell 20150501 5
It has long been the dream of biologists to map gene expression at the single-cell level. With such data one might track heterogeneous cell sub-populations, and infer regulatory relationships between genes and pathways. Recently, RNA sequencing has achieved single-cell resolution. What is limiting is an effective way to routinely isolate and process large numbers of individual cells for quantitative in-depth sequencing. We have developed a high-throughput droplet-microfluidic approach for barcod ...[more]