Unknown

Dataset Information

0

Optimizing treatments for anxiety by age and genetics.


ABSTRACT: This paper highlights recent human neuroimaging and cross-species developmental and genetic studies that examine how fear regulation varies by age and the individual, especially during the period of adolescence, when there is a peak in the prevalence of anxiety disorders. The findings have significant implications for understanding who may be at risk for anxiety disorders and for whom, and when, an exposure-based therapy may be most effective. We provide proof of concept for targeting treatment to the individual as a function of age and genetics, inferred from mouse and human studies, and suggest optimization of treatment for nonresponders.

SUBMITTER: Casey BJ 

PROVIDER: S-EPMC4447548 | biostudies-literature | 2015 May

REPOSITORIES: biostudies-literature

altmetric image

Publications

Optimizing treatments for anxiety by age and genetics.

Casey B J BJ   Lee Francis S FS  

Annals of the New York Academy of Sciences 20150319


This paper highlights recent human neuroimaging and cross-species developmental and genetic studies that examine how fear regulation varies by age and the individual, especially during the period of adolescence, when there is a peak in the prevalence of anxiety disorders. The findings have significant implications for understanding who may be at risk for anxiety disorders and for whom, and when, an exposure-based therapy may be most effective. We provide proof of concept for targeting treatment  ...[more]

Similar Datasets

| S-EPMC7056640 | biostudies-literature
| S-EPMC3340784 | biostudies-literature
| S-EPMC6246001 | biostudies-literature
| S-EPMC3721501 | biostudies-literature
| S-EPMC2760665 | biostudies-literature
| S-EPMC5606891 | biostudies-literature
| S-EPMC5573560 | biostudies-literature
| S-EPMC5734112 | biostudies-literature
| S-EPMC3655048 | biostudies-literature
| S-EPMC5349709 | biostudies-literature