Ontology highlight
ABSTRACT:
SUBMITTER: Khaleel A
PROVIDER: S-EPMC4452106 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Khaleel Anas A Wu Mei-Shin MS Wong Henry Sung-Ching HS Hsu Yu-Wen YW Chou Yii-Her YH Chen Hsiang-Yin HY Chen Hsiang-Yin HY
Mediators of inflammation 20150518
Nephrolithiasis is characterized by calcification of stones in the kidneys from an unknown cause. Animal models demonstrated the functional roles of the transient receptor potential vanilloid member 5 (TRPV5) gene in calcium renal reabsorption and hypercalciuria. Therefore, TRPV5 was suggested to be involved in calcium homeostasis. However, whether genetic polymorphisms of TRPV5 are associated with kidney stone multiplicity or recurrence is unclear. In this study, 365 Taiwanese kidney-stone pati ...[more]