Ontology highlight
ABSTRACT:
SUBMITTER: Liu J
PROVIDER: S-EPMC6418352 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Liu Jiting J Zhang Li L Feng Lixia L Xu Ming M Gao Yue Y Zhou Peng P Yu Zhengmin Z Zhu Baoli B An Yan Y Zhang Hengdong H
Molecular genetics & genomic medicine 20190121 3
<h4>Background</h4>Lead (Pb) is broadly used in various industries and causes irreversible damage to human tissues, organs, and systems. Studies have revealed that lead exerts toxic effects via interfering with calcium channel.<h4>Methods</h4>In the present study, we investigated whether single nucleotide polymorphisms (SNPs) in TRPV5, a calcium channel-related gene, were associated with lead exposure susceptibility. By using TaqMan SNP genotyping, we performed genotyping of eight TRPV5 tag-SNPs ...[more]