Ontology highlight
ABSTRACT:
SUBMITTER: Sproul CD
PROVIDER: S-EPMC4454621 | biostudies-literature | 2014 Jan
REPOSITORIES: biostudies-literature
Sproul Christopher D CD Mitchell David L DL Rao Shangbang S Ibrahim Joseph G JG Kaufmann William K WK Cordeiro-Stone Marila M
Photochemistry and photobiology 20131128 1
This study compared biological responses of normal human fibroblasts (NHF1) to three sources of ultraviolet radiation (UVR), emitting UVC wavelengths, UVB wavelengths, or a combination of UVA and UVB (solar simulator; emission spectrum, 94.3% UVA and 5.7% UVB). The endpoints measured were cytotoxicity, intra-S checkpoint activation, inhibition of DNA replication and mutagenicity. Results show that the magnitude of each response to the indicated radiation sources was best predicted by the density ...[more]