Genetic encoding of the post-translational modification 2-hydroxyisobutyryl-lysine.
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ABSTRACT:
SUBMITTER: Knight WA
PROVIDER: S-EPMC4457286 | biostudies-literature | 2015 Jun
REPOSITORIES: biostudies-literature
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Genetic encoding of the post-translational modification 2-hydroxyisobutyryl-lysine.
Knight William A WA Cropp T Ashton TA
Organic & biomolecular chemistry 20150522 23
We report the synthesis and genetic encoding of a recently discovered post-translational modification, 2-hydroxyisobutyryl-lysine, to the genetic code of E. coli. The production of homogeneous proteins containing this amino acid will facilitate the study of modification in full-length proteins. ...[more]
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