Ontology highlight
ABSTRACT:
SUBMITTER: Truman AW
PROVIDER: S-EPMC4459869 | biostudies-literature | 2015 Mar
REPOSITORIES: biostudies-literature
Truman Andrew W AW Kristjansdottir Kolbrun K Wolfgeher Donald D Ricco Natalia N Mayampurath Anoop A Volchenboum Samuel L SL Clotet Josep J Kron Stephen J SJ
Data in brief 20141107
The molecular chaperones Hsp70 and Hsp90 participate in many important cellular processes, including how cells respond to DNA damage. Here we show the results of applied quantitative affinity-purification mass spectrometry (AP-MS) proteomics to understand the protein network through which Hsp70 and Hsp90 exert their effects on the DNA damage response (DDR). We characterized the interactomes of the yeast Hsp70 isoform Ssa1 and Hsp90 isoform Hsp82 before and after exposure to methyl methanesulfona ...[more]