Ontology highlight
ABSTRACT:
SUBMITTER: Bousman CA
PROVIDER: S-EPMC4461056 | biostudies-literature | 2010 Oct
REPOSITORIES: biostudies-literature
Bousman Chad A CA Chana Gursharan G Glatt Stephen J SJ Chandler Sharon D SD May Todd T Lohr James J Kremen William S WS Tsuang Ming T MT Everall Ian P IP
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 20101001 7
Several brain- and blood-based gene expression studies in patients with psychotic disorders (e.g., schizophrenia) have identified genes in the ubiquitin proteasome system (UPS) pathway as putative biomarkers. However, to date an examination of the UPS pathway in the broader context of symptom severity in psychosis has not been conducted. The purpose of this study was to investigate the correlation between clinical scores on the Scales for the Assessment of Positive and Negative Symptoms (SAPS-SA ...[more]