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Fatal Human Meningoencephalitis due to Halicephalobus Nematodes, Germany.

ABSTRACT: Infections with Halicephalobus nematodes, causative agents of severe meningoencephalitis in horses, have rarely been reported in humans. In this study, the clinical, serological, cytokine, and histopathological findings of a rapidly progressive and eventually fatal meningoencephalitis in a previously healthy human are described. The helminth was finally diagnosed by specific polymerase chain reactions from post mortem tissue.

SUBMITTER: Monoranu CM

PROVIDER: S-EPMC4462890 | biostudies-literature | 2015 Apr

REPOSITORIES: biostudies-literature

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Fatal Human Meningoencephalitis due to Halicephalobus Nematodes, Germany.

Monoranu Camelia-Maria CM Müllges Wolfgang W Keppler Marc M Brehm Klaus K Ondrejka Sarah L SL Muntau Birgit B Tannich Egbert E Müller-Hermelink Hans Konrad HK Tappe Dennis D

Open forum infectious diseases 20150401 2

Infections with Halicephalobus nematodes, causative agents of severe meningoencephalitis in horses, have rarely been reported in humans. In this study, the clinical, serological, cytokine, and histopathological findings of a rapidly progressive and eventually fatal meningoencephalitis in a previously healthy human are described. The helminth was finally diagnosed by specific polymerase chain reactions from post mortem tissue. ...[more]

PMID: 26125032

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