Ontology highlight
ABSTRACT:
SUBMITTER: Wang C
PROVIDER: S-EPMC4466219 | biostudies-literature | 2015 Sep
REPOSITORIES: biostudies-literature
Wang Cheng C Kim Jinho J Zhu Yibo Y Yang Jaeyoung J Lee Gwan-Hyoung GH Lee Sunwoo S Yu Jaeeun J Pei Renjun R Liu Guohua G Nuckolls Colin C Hone James J Lin Qiao Q
Biosensors & bioelectronics 20150413
This paper presents an aptameric graphene nanosensor for detection of small-molecule biomarkers. To address difficulties in direct detection of small molecules associated with their low molecular weight and electrical charge, we incorporate an aptamer-based competitive affinity assay in a graphene field effect transistor (FET), and demonstrate the utility of the nanosensor with dehydroepiandrosterone sulfate (DHEA-S), a small-molecule steroid hormone, as the target analyte. In the competitive af ...[more]