Ontology highlight
ABSTRACT:
SUBMITTER: Hindler JA
PROVIDER: S-EPMC4468720 | biostudies-literature | 2015 Jul
REPOSITORIES: biostudies-literature
Hindler Janet A JA Wong-Beringer Annie A Charlton Carmen L CL Miller Shelley A SA Kelesidis Theodoros T Carvalho Marissa M Sakoulas George G Nonejuie Poochit P Pogliano Joseph J Nizet Victor V Humphries Romney R
Antimicrobial agents and chemotherapy 20150511 7
Enterococci that are nonsusceptible (NS; MIC > 4 μg/ml) to daptomycin are an emerging clinical concern. The synergistic combination of daptomycin plus beta-lactams has been shown to be effective against vancomycin-resistant Enterococcus (VRE) species in vitro. This study systematically evaluated by in vitro time-kill studies the effect of daptomycin in combination with ampicillin, cefazolin, ceftriaxone, ceftaroline, ertapenem, gentamicin, tigecycline, and rifampin, for a collection of 9 daptomy ...[more]