Ontology highlight
ABSTRACT:
SUBMITTER: Ishikawa M
PROVIDER: S-EPMC4471747 | biostudies-literature | 2015 Aug
REPOSITORIES: biostudies-literature
Ishikawa Masashi M Takai Masahiko M Maeda Hajime H Kanamori Akira A Kubota Akira A Amemiya Hikaru H Iizuka Takashi T Iemitsu Kotaro K Iwasaki Tomoyuki T Uehara Goro G Umezawa Shinichi S Obana Mitsuo M Kaneshige Hideaki H Kaneshiro Mizuki M Kawata Takehiro T Sasai Nobuo N Saito Tatsuya T Takuma Tetsuo T Takeda Hiroshi H Tanaka Keiji K Tsurui Nobuaki N Nakajima Shigeru S Hoshino Kazuhiko K Honda Shin S Machimura Hideo H Matoba Kiyokazu K Minagawa Fuyuki F Minami Nobuaki N Miyairi Yukiko Y Mokubo Atsuko A Motomiya Tetsuya T Waseda Manabu M Miyakawa Masaaki M Naka Yoshikazu Y Terauchi Yasuo Y Tanaka Yasushi Y Matsuba Ikuro I
Journal of clinical medicine research 20150609 8
<h4>Background</h4>It is unclear whether dipeptidyl peptidase-4 inhibitors decrease hemoglobin A1c (HbA1c) in a glucose-dependent manner in patients on insulin therapy who have impaired insulin secretion. This study investigated factors influencing the efficacy of sitagliptin when used concomitantly with insulin to treat type 2 diabetes mellitus (T2DM) in the real-world setting.<h4>Methods</h4>A retrospective study was conducted of 1,004 T2DM patients at 36 Japanese clinics associated with the D ...[more]