Ontology highlight
ABSTRACT:
SUBMITTER: Guo J
PROVIDER: S-EPMC4472062 | biostudies-literature | 2015 Jun
REPOSITORIES: biostudies-literature
Guo Jingjing J Zhou Huan-Xiang HX
Biophysical journal 20150601 12
There is considerable interest in the dynamic aspect of allosteric action, and in a growing list of proteins allostery has been characterized as being mediated predominantly by a change in dynamics, not a transition in conformation. For considering conformational dynamics, a protein molecule can be simplified into a number of relatively rigid microdomains connected by joints, corresponding to, e.g., communities and edges from a community network analysis. Binding of an allosteric activator stren ...[more]