Ontology highlight
ABSTRACT:
SUBMITTER: Bonamassa B
PROVIDER: S-EPMC4472997 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Bonamassa Barbara B Ciccarese Francesco F Antonio Veronica Di VD Contarini Andrea A Palù Giorgio G Alvisi Gualtiero G
Frontiers in microbiology 20150619
There is growing evidence that factors encoded by cytoplasmic replicating viruses functionally interact with components of the nucleocytoplasmic transport apparatus. They do so either to access the cell nucleus, thus affecting genes expression, or to interfere with nuclear transport functionality, hindering host immune response. Recent studies revealed that the hepatitis C virus (HCV) makes no exception, interacting with the host cell nuclear transport machinery at two different levels. On the o ...[more]