Ontology highlight
ABSTRACT:
SUBMITTER: Arimbasseri AG
PROVIDER: S-EPMC4475470 | biostudies-literature | 2015 Jun
REPOSITORIES: biostudies-literature
Arimbasseri Aneeshkumar G AG Maraia Richard J RJ
Molecular cell 20150507 6
Understanding the mechanism of transcription termination by a eukaryotic RNA polymerase (RNAP) has been limited by lack of a characterizable intermediate that reflects transition from an elongation complex to a true termination event. While other multisubunit RNAPs require multipartite cis-signals and/or ancillary factors to mediate pausing and release of the nascent transcript from the clutches of these enzymes, RNAP III does so with precision and efficiency on a simple oligo(dT) tract, indepen ...[more]