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Biotechnological Aspects and Perspective of Microbial Keratinase Production.

ABSTRACT: Keratinases are proteolytic enzymes predominantly active when keratin substrates are available that attack disulfide bridges in the keratin to convert them from complex to simplified forms. Keratinases are essential in preparation of animal nutrients, protein supplements, leather manufacture, textile processing, detergent formulation, feather meal processing for feed and fertilizer, the pharmaceutical and biomedical industries, and waste management. Accordingly, it is necessary to develop a method for continuous production of keratinase from reliable sources that can be easily managed. Microbial keratinase is less expensive than conventionally produced keratinase and can be obtained from fungi, bacteria, and actinomycetes. In this overview, the expansion of information about microbial keratinases and important considerations in keratinase production are discussed.

SUBMITTER: Gopinath SC

PROVIDER: S-EPMC4477050 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature

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Biotechnological Aspects and Perspective of Microbial Keratinase Production.

Gopinath Subash C B SC Anbu Periasamy P Lakshmipriya Thangavel T Tang Thean-Hock TH Chen Yeng Y Hashim Uda U Ruslinda A Rahim AR Arshad M K Md MK

BioMed research international 20150609

Keratinases are proteolytic enzymes predominantly active when keratin substrates are available that attack disulfide bridges in the keratin to convert them from complex to simplified forms. Keratinases are essential in preparation of animal nutrients, protein supplements, leather manufacture, textile processing, detergent formulation, feather meal processing for feed and fertilizer, the pharmaceutical and biomedical industries, and waste management. Accordingly, it is necessary to develop a meth ...[more]

PMID: 26180780

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