Ontology highlight
ABSTRACT:
SUBMITTER: Cheng T
PROVIDER: S-EPMC4481175 | biostudies-literature | 2015 Jul
REPOSITORIES: biostudies-literature
Cheng Tian T Yang Bo B Li Dongpeng D Ma Shanshan S Tian Yi Y Qu Ruina R Zhang Wenjin W Zhang Yanting Y Hu Kai K Guan Fangxia F Wang Jian J
Cellular and molecular neurobiology 20150201 5
Traumatic brain injury (TBI), which can lead to disability, dysfunction, and even death, is a prominent health problem worldwide. Effective therapy for this serious and debilitating condition is needed. Human umbilical cord matrix, known as Wharton's jelly (WJ), provides a natural, interface scaffold that is enriched in mesenchymal stem cells. In this study, we tested the efficacy of WJ tissue transplantation in a weight-drop model of TBI in rats. WJ tissue was cultured and transplanted into the ...[more]