Ontology highlight
ABSTRACT:
SUBMITTER: Holmes K
PROVIDER: S-EPMC4481223 | biostudies-literature | 2015 Jun
REPOSITORIES: biostudies-literature
The Journal of biological chemistry 20150507 26
Macromolecular complexes are responsible for many key biological processes. However, in most cases details of the assembly/disassembly of such complexes are unknown at the molecular level, as the low abundance and transient nature of assembly intermediates make analysis challenging. The assembly of virus capsids is an example of such a process. The hepatitis B virus capsid (core) can be composed of either 90 or 120 dimers of coat protein. Previous studies have proposed a trimer of dimers as an i ...[more]