Hepatitis C virus: assembly and release of virus particles.
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ABSTRACT:
SUBMITTER: Jones DM
PROVIDER: S-EPMC2906262 | biostudies-literature | 2010 Jul
REPOSITORIES: biostudies-literature
Publications
Hepatitis C virus: assembly and release of virus particles.
Jones Daniel M DM McLauchlan John J
The Journal of biological chemistry 20100510 30
Hepatitis C virus is a blood-borne virus that typically establishes a chronic infection in the liver, which often results in cirrhosis and hepatocellular carcinoma. Progress in understanding the complete virus life cycle has been greatly enhanced by the recent availability of a tissue culture system that produces infectious virus progeny. Thus, it is now possible to gain insight into the roles played by viral components in assembly and egress and the cellular pathways that contribute to virion f ...[more]
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