Ontology highlight
ABSTRACT:
SUBMITTER: Curtis-Fisk J
PROVIDER: S-EPMC4485613 | biostudies-literature | 2008 Sep
REPOSITORIES: biostudies-literature
Curtis-Fisk Jaime J Spencer Ryan M RM Weliky David P DP
Journal of the American Chemical Society 20080829 38
Inclusion bodies are insoluble aggregates that are formed by bacteria to store excess recombinant protein produced during expression. The structure of the protein in inclusion bodies is poorly understood but it has been hypothesized that the protein may form misfolded beta sheet aggregates. This paper presents an isotopic labeling and solid-state nuclear magnetic resonance approach to determine the secondary structure of individual residues within a recombinant influenza virus "FHA2" protein in ...[more]