Ontology highlight
ABSTRACT:
SUBMITTER: Hui R
PROVIDER: S-EPMC4485940 | biostudies-literature | 2015 Jul
REPOSITORIES: biostudies-literature
Trends in pharmacological sciences 20150520 7
Apicomplexan parasites cause some of the most severe human diseases, including malaria (caused by Plasmodium), toxoplasmosis, and cryptosporidiosis. Treatments are limited by the lack of effective drugs and development of resistance to available agents. By exploiting novel features of protein kinases in these parasites, it may be possible to develop new treatments. We summarize here recent advances in identifying small molecule inhibitors against a novel family of plant-like, calcium-dependent k ...[more]