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Long and short lipid molecules experience the same interleaflet drag in lipid bilayers.

ABSTRACT: Membrane interleaflet viscosity ?e affects tether formation, phase separation into domains, cell shape changes, and budding. Contrary to the expected contribution to interleaflet coupling from interdigitation, the slide of lipid patches in opposing monolayers conferred the same value ?e?3×10(9)??J?s?m-4 for the friction experienced by the ends of both short and long chain fluorescent lipid analogues. Consistent with the weak dependence of the translational diffusion coefficient on lipid length, the in-layer viscosity was, albeit length dependent, much smaller than ?e.

SUBMITTER: Horner A

PROVIDER: S-EPMC4486369 | biostudies-literature | 2013 Jun

REPOSITORIES: biostudies-literature

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Long and short lipid molecules experience the same interleaflet drag in lipid bilayers.

Horner Andreas A Akimov Sergey A SA Pohl Peter P

Physical review letters 20130624 26

Membrane interleaflet viscosity ηe affects tether formation, phase separation into domains, cell shape changes, and budding. Contrary to the expected contribution to interleaflet coupling from interdigitation, the slide of lipid patches in opposing monolayers conferred the same value ηe≈3×10(9) J s m-4 for the friction experienced by the ends of both short and long chain fluorescent lipid analogues. Consistent with the weak dependence of the translational diffusion coefficient on lipid length, ...[more]

PMID: 23848924

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