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Bladder reconstruction: The past, present and future.


ABSTRACT: Ileal conduit urinary diversion is the gold standard treatment for urinary tract reconstruction following cystectomy. This procedure uses gastrointestinal segments for bladder augmentation, a technique that is often associated with significant complications. The substantial progression in the fields of tissue engineering and regenerative medicine over the previous two decades has resulted in the development of techniques that may lead to the construction of functional de novo urinary bladder substitutes. The present review identifies and discusses the complications associated with current treatment options post-cystectomy. The current techniques, achievements and perspectives of the use of biomaterials and stem cells in the field of urinary bladder reconstruction are also reviewed.

SUBMITTER: El-Taji OM 

PROVIDER: S-EPMC4487078 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature

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Bladder reconstruction: The past, present and future.

El-Taji Omar M S OM   Khattak Altaf Q AQ   Hussain Syed A SA  

Oncology letters 20150428 1


Ileal conduit urinary diversion is the gold standard treatment for urinary tract reconstruction following cystectomy. This procedure uses gastrointestinal segments for bladder augmentation, a technique that is often associated with significant complications. The substantial progression in the fields of tissue engineering and regenerative medicine over the previous two decades has resulted in the development of techniques that may lead to the construction of functional <i>de novo</i> urinary blad  ...[more]

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