Ontology highlight
ABSTRACT:
SUBMITTER: Jenjaroenpun P
PROVIDER: S-EPMC4489302 | biostudies-literature | 2015 Jul
REPOSITORIES: biostudies-literature
Jenjaroenpun Piroon P Wongsurawat Thidathip T Yenamandra Surya Pavan SP Kuznetsov Vladimir A VA
Nucleic acids research 20150416 W1
The possible formation of three-stranded RNA and DNA hybrid structures (R-loops) in thousands of functionally important guanine-rich genic and inter-genic regions could suggest their involvement in transcriptional regulation and even development of diseases. Here, we introduce the first freely available R-loop prediction program called Quantitative Model of R-loop Forming Sequence (RLFS) finder (QmRLFS-finder), which predicts RLFSs in nucleic acid sequences based on experimentally supported stru ...[more]