Ontology highlight
ABSTRACT:
SUBMITTER: Miller CR
PROVIDER: S-EPMC4490025 | biostudies-literature | 2015 Jul
REPOSITORIES: biostudies-literature
British journal of haematology 20150419 2
A jumping translocation (JT) is a rare cytogenetic aberration that can occur in haematological malignancy. It involves the translocation of the same fragment of donor chromosome onto two or more recipient chromosomes, typically in different cells. In this study, we describe the first series of chronic lymphocytic leukaemia (CLL) patients with JTs reported to date. Following a review of 878 CLL patient karyotypes, we identified 26 patients (3%) with 97 JTs. The most commonly occurring breakpoint ...[more]