Ontology highlight
ABSTRACT:
SUBMITTER: Hazan-Halevy I
PROVIDER: S-EPMC4490183 | biostudies-literature | 2015 Aug
REPOSITORIES: biostudies-literature
Hazan-Halevy Inbal I Rosenblum Daniel D Weinstein Shiri S Bairey Osnat O Raanani Pia P Peer Dan D Peer Dan D
Cancer letters 20150428 1
Mantle cell lymphoma (MCL) is an aggressive and incurable mature B cell neoplasm. The current treatments are based on chemotherapeutics and new class of drugs (e.g. Ibrutinib(®)), which in most cases ends with tumor resistance and relapse. Therefore, further development of novel therapeutic modalities is needed. Exosomes are natural extracellular vesicles, which play an important role in intercellular communication. The specificity of exosome uptake by different target cells remains unknown. In ...[more]