Uptake of lymphoma-derived exosomes by peripheral blood leukocytes.
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ABSTRACT:
SUBMITTER: Ferguson Bennit HR
PROVIDER: S-EPMC6467345 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Publications
Uptake of lymphoma-derived exosomes by peripheral blood leukocytes.
Ferguson Bennit Heather R HR Gonda Amber A Oppegard Laura J LJ Chi David P DP Khan Salma S Wall Nathan R NR
Blood and lymphatic cancer : targets and therapy 20170228
Exosomes are nanosized lipid vesicles secreted into blood and other body fluids and serve as vehicles for intercellular communication. Despite being an important component of the tumor microenvironment (TME), exosomal targeting and uptake into recipient cells are still not fully understood. Few studies have looked at lymphoma exosomes and their interactions with circulating blood cells. In this study, we examine the exosomal uptake distribution among peripheral blood leukocytes (PBLs) using vesi ...[more]
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