Ontology highlight
ABSTRACT:
SUBMITTER: Rigoli JW
PROVIDER: S-EPMC4492479 | biostudies-literature | 2013 Nov
REPOSITORIES: biostudies-literature
Journal of the American Chemical Society 20131111 46
Organic N-containing compounds, including amines, are essential components of many biologically and pharmaceutically important molecules. One strategy for introducing nitrogen into substrates with multiple reactive bonds is to insert a monovalent N fragment (nitrene or nitrenoid) into a C-H bond or add it directly to a C═C bond. However, it has been challenging to develop well-defined catalysts capable of promoting predictable and chemoselective aminations solely through reagent control. Herein, ...[more]