Ligand-controlled, tunable silver-catalyzed C-H amination.

ABSTRACT: The development of readily tunable and regioselective C-H functionalization reactions that operate solely through catalyst control remains a challenge in modern organic synthesis. Herein, we report that simple silver catalysts supported by common nitrogenated ligands can be used to tune a nitrene transfer reaction between two different types of C-H bonds. The results reported herein represent the first example of ligand-controlled and site-selective silver-promoted C-H amination.

SUBMITTER: Alderson JM 

PROVIDER: S-EPMC4277762 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature