Ontology highlight
ABSTRACT:
SUBMITTER: Cox DB
PROVIDER: S-EPMC4492683 | biostudies-literature | 2015 Feb
REPOSITORIES: biostudies-literature
Cox David Benjamin Turitz DB Platt Randall Jeffrey RJ Zhang Feng F
Nature medicine 20150201 2
Recent advances in the development of genome editing technologies based on programmable nucleases have substantially improved our ability to make precise changes in the genomes of eukaryotic cells. Genome editing is already broadening our ability to elucidate the contribution of genetics to disease by facilitating the creation of more accurate cellular and animal models of pathological processes. A particularly tantalizing application of programmable nucleases is the potential to directly correc ...[more]