Ontology highlight
ABSTRACT:
SUBMITTER: Cremona A
PROVIDER: S-EPMC4493071 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
PloS one 20150706 7
The formation of lipid microdomains ("rafts") is presumed to play an important role in various cellular functions, but their nature remains controversial. Here we report on microdomain formation in isolated, detergent-resistant membranes from MDA-MB-231 human breast cancer cells, studied by atomic force microscopy (AFM). Whereas microdomains were readily observed at room temperature, they shrunk in size and mostly disappeared at higher temperatures. This shrinking in microdomain size was accompa ...[more]