Ontology highlight
ABSTRACT:
SUBMITTER: Castro NP
PROVIDER: S-EPMC4494913 | biostudies-literature | 2015 May
REPOSITORIES: biostudies-literature
Castro Nadia P NP Fedorova-Abrams Natalie D ND Merchant Anand S AS Rangel Maria Cristina MC Nagaoka Tadahiro T Karasawa Hideaki H Klauzinska Malgorzata M Hewitt Stephen M SM Biswas Kajal K Sharan Shyam K SK Salomon David S DS
Oncotarget 20150501 14
Triple-negative breast cancer (TNBC) presents the poorest prognosis among the breast cancer subtypes and no current standard therapy. Here, we performed an in-depth molecular analysis of a mouse model that establishes spontaneous lung metastasis from JygMC(A) cells. These primary tumors resembled the triple-negative breast cancer (TNBC) both phenotypically and molecularly. Morphologically, primary tumors presented both epithelial and spindle-like cells but displayed only adenocarcinoma-like feat ...[more]