Ontology highlight
ABSTRACT:
SUBMITTER: Marin-Aguilera M
PROVIDER: S-EPMC4496379 | biostudies-literature | 2015 Apr
REPOSITORIES: biostudies-literature
Marín-Aguilera Mercedes M Reig Òscar Ò Lozano Juan José JJ Jiménez Natalia N García-Recio Susana S Erill Nadina N Gaba Lydia L Tagliapietra Andrea A Ortega Vanesa V Carrera Gemma G Colomer Anna A Gascón Pedro P Mellado Begoña B
Oncotarget 20150401 12
The enumeration of circulating tumor cells (CTCs) in peripheral blood correlates with clinical outcome in castration-resistant prostate cancer (CRPC). We analyzed the molecular profiling of peripheral blood from 43 metastatic CRPC patients with known CTC content in order to identify genes that may be related to prostate cancer progression. Global gene expression analysis identified the differential expression of 282 genes between samples with ≥5 CTCs vs <5 CTCs, 58.6% of which were previously de ...[more]