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First report of autochthonous transmission of Zika virus in Brazil.

ABSTRACT: In the early 2015, several cases of patients presenting symptoms of mild fever, rash, conjunctivitis and arthralgia were reported in the northeastern Brazil. Although all patients lived in a dengue endemic area, molecular and serological diagnosis for dengue resulted negative. Chikungunya virus infection was also discarded. Subsequently, Zika virus (ZIKV) was detected by reverse transcription-polymerase chain reaction from the sera of eight patients and the result was confirmed by DNA sequencing. Phylogenetic analysis suggests that the ZIKV identified belongs to the Asian clade. This is the first report of ZIKV infection in Brazil.

SUBMITTER: Zanluca C

PROVIDER: S-EPMC4501423 | biostudies-literature | 2015 Jun

REPOSITORIES: biostudies-literature

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First report of autochthonous transmission of Zika virus in Brazil.

Zanluca Camila C Melo Vanessa Campos Andrade de VC Mosimann Ana Luiza Pamplona AL Santos Glauco Igor Viana Dos GI Santos Claudia Nunes Duarte Dos CN Luz Kleber K

Memorias do Instituto Oswaldo Cruz 20150609 4

In the early 2015, several cases of patients presenting symptoms of mild fever, rash, conjunctivitis and arthralgia were reported in the northeastern Brazil. Although all patients lived in a dengue endemic area, molecular and serological diagnosis for dengue resulted negative. Chikungunya virus infection was also discarded. Subsequently, Zika virus (ZIKV) was detected by reverse transcription-polymerase chain reaction from the sera of eight patients and the result was confirmed by DNA sequencing ...[more]

PMID: 26061233

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