Ontology highlight
ABSTRACT:
SUBMITTER: Greco SH
PROVIDER: S-EPMC4501823 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Greco Stephanie H SH Tomkötter Lena L Vahle Anne-Kristin AK Rokosh Rae R Avanzi Antonina A Mahmood Syed Kashif SK Deutsch Michael M Alothman Sara S Alqunaibit Dalia D Ochi Atsuo A Zambirinis Constantinos C Mohaimin Tasnima T Rendon Mauricio M Levie Elliot E Pansari Mridul M Torres-Hernandez Alejandro A Daley Donnele D Barilla Rocky R Pachter H Leon HL Tippens Daniel D Malik Hassan H Boutajangout Allal A Wisniewski Thomas T Miller George G
PloS one 20150714 7
Cancer cachexia is a debilitating condition characterized by a combination of anorexia, muscle wasting, weight loss, and malnutrition. This condition affects an overwhelming majority of patients with pancreatic cancer and is a primary cause of cancer-related death. However, few, if any, effective therapies exist for both treatment and prevention of this syndrome. In order to develop novel therapeutic strategies for pancreatic cancer cachexia, appropriate animal models are necessary. In this stud ...[more]