Epigenome data release: a participant-centered approach to privacy protection.
Ontology highlight
ABSTRACT:
SUBMITTER: Dyke SO
PROVIDER: S-EPMC4504083 | biostudies-literature | 2015 Jul
REPOSITORIES: biostudies-literature
Publications
Epigenome data release: a participant-centered approach to privacy protection.
Dyke Stephanie O M SO Cheung Warren A WA Joly Yann Y Ammerpohl Ole O Lutsik Pavlo P Rothstein Mark A MA Caron Maxime M Busche Stephan S Bourque Guillaume G Rönnblom Lars L Flicek Paul P Beck Stephan S Hirst Martin M Stunnenberg Henk H Siebert Reiner R Walter Jörn J Pastinen Tomi T
Genome biology 20150717
Large-scale epigenome mapping by the NIH Roadmap Epigenomics Project, the ENCODE Consortium and the International Human Epigenome Consortium (IHEC) produces genome-wide DNA methylation data at one base-pair resolution. We examine how such data can be made open-access while balancing appropriate interpretation and genomic privacy. We propose guidelines for data release that both reduce ambiguity in the interpretation of open-access data and limit immediate access to genetic variation data that ar ...[more]
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