PLA2-responsive and SPIO-loaded phospholipid micelles.
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ABSTRACT:
SUBMITTER: Gao Q
PROVIDER: S-EPMC4506235 | biostudies-literature | 2015 Aug
REPOSITORIES: biostudies-literature
Publications
PLA2-responsive and SPIO-loaded phospholipid micelles.
Gao Qiang Q Yan Lesan L Chiorazzo Michael M Delikatny E James EJ Tsourkas Andrew A Cheng Zhiliang Z
Chemical communications (Cambridge, England) 20150801 61
PLA2-responsive and superparamagnetic iron oxide (SPIO) nanoparticle-loaded phospholipid micelles were developed. The release of a phospholipid-conjugated dye from these micelles was triggered due to phospholipid degradation by phospholipase A2. The high relaxivity of the encapsulated SPIO could enable non-invasive magnetic resonance imaging. ...[more]
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