Ontology highlight
ABSTRACT:
SUBMITTER: Shaytan AK
PROVIDER: S-EPMC4512853 | biostudies-literature | 2015 Jun
REPOSITORIES: biostudies-literature
Shaytan Alexey K AK Landsman David D Panchenko Anna R AR
Current opinion in structural biology 20150227
Nucleosome variability is essential for their functions in compacting the chromatin structure and regulation of transcription, replication and cell reprogramming. The DNA molecule in nucleosomes is wrapped around an octamer composed of four types of core histones (H3, H4, H2A, H2B). Nucleosomes represent dynamic entities and may change their conformation, stability and binding properties by employing different sets of histone variants or by becoming post-translationally modified. There are many ...[more]