Ontology highlight
ABSTRACT:
SUBMITTER: Shi Z
PROVIDER: S-EPMC4513854 | biostudies-literature | 2015 Jul
REPOSITORIES: biostudies-literature
Shi Zhongcheng Z Chiang Chi-I CI Labhart Paul P Zhao Yanling Y Yang Jianhua J Mistretta Toni-Ann TA Henning Susan J SJ Maity Sankar N SN Mori-Akiyama Yuko Y
Nucleic acids research 20150603 13
Roles for SOX9 have been extensively studied in development and particular emphasis has been placed on SOX9 roles in cell lineage determination in a number of discrete tissues. Aberrant expression of SOX9 in many cancers, including colorectal cancer, suggests roles in these diseases as well and recent studies have suggested tissue- and context-specific roles of SOX9. Our genome wide approach by chromatin immunoprecipitation sequencing (ChIP-seq) in human colorectal cancer cells identified a numb ...[more]