Ontology highlight
ABSTRACT:
SUBMITTER: Gordon PM
PROVIDER: S-EPMC4519388 | biostudies-literature | 2015 Jul
REPOSITORIES: biostudies-literature
Gordon Patricia M PM Hobert Oliver O
Developmental cell 20150618 2
Neuron identity transformations occur upon removal of specific regulatory factors in many different cellular contexts, thereby revealing the fundamental principle of alternative cell identity choices made during nervous system development. One common molecular interpretation of such homeotic cell identity transformations is that a regulatory factor has a dual function in activating genes defining one cellular identity and repressing genes that define an alternative identity. We provide evidence ...[more]