Ontology highlight
ABSTRACT:
SUBMITTER: Weber BS
PROVIDER: S-EPMC4522760 | biostudies-literature | 2015 Jul
REPOSITORIES: biostudies-literature
Weber Brent S BS Ly Pek Man PM Irwin Joshua N JN Pukatzki Stefan S Feldman Mario F MF
Proceedings of the National Academy of Sciences of the United States of America 20150713 30
Infections with Acinetobacter baumannii, one of the most troublesome and least studied multidrug-resistant superbugs, are increasing at alarming rates. A. baumannii encodes a type VI secretion system (T6SS), an antibacterial apparatus of Gram-negative bacteria used to kill competitors. Expression of the T6SS varies among different strains of A. baumannii, for which the regulatory mechanisms are unknown. Here, we show that several multidrug-resistant strains of A. baumannii harbor a large, self-t ...[more]