Ontology highlight
ABSTRACT:
SUBMITTER: Pullen TJ
PROVIDER: S-EPMC452581 | biostudies-literature | 2004 Jul
REPOSITORIES: biostudies-literature
Pullen Timothy J TJ Ginger Michael L ML Gaskell Simon J SJ Gull Keith K
Molecular biology of the cell 20040514 7
The eukaryotic flagellum is a large structure into which specific constituent proteins must be targeted, transported and assembled after their synthesis in the cytoplasm. Using Trypanosoma brucei and a proteomic approach, we have identified and characterized a novel set of adenylate kinase proteins that are localized to the flagellum. These proteins represent unique isoforms that are targeted to the flagellum by an N-terminal extension to the protein and are incorporated into an extraaxonemal st ...[more]