Ontology highlight
ABSTRACT:
SUBMITTER: Perugorria MJ
PROVIDER: S-EPMC4526263 | biostudies-literature | 2014 Dec
REPOSITORIES: biostudies-literature
Perugorria Maria J MJ Masyuk Tatyana V TV Marin Jose J JJ Marzioni Marco M Bujanda Luis L LaRusso Nicholas F NF Banales Jesus M JM
Nature reviews. Gastroenterology & hepatology 20140930 12
Polycystic liver diseases are genetic disorders characterized by progressive bile duct dilatation and/or cyst development. The large volume of hepatic cysts causes different symptoms and complications such as abdominal distension, local pressure with back pain, hypertension, gastro-oesophageal reflux and dyspnea as well as bleeding, infection and rupture of the cysts. Current therapeutic strategies are based on surgical procedures and pharmacological management, which partially prevent or amelio ...[more]