Ontology highlight
ABSTRACT:
SUBMITTER: Li L
PROVIDER: S-EPMC4528334 | biostudies-literature | 2015 Jun
REPOSITORIES: biostudies-literature
Li Lihong L Miles Shawna S Breeden Linda L LL
G3 (Bethesda, Md.) 20150610 8
Budding yeast begin the transition to quiescence by prolonging G1 and accumulating limited nutrients. They undergo asymmetric cell divisions, slow cellular expansion, acquire significant stress tolerance and construct elaborate cell walls. These morphologic changes give rise to quiescent (Q) cells, which can be distinguished from three other cell types in a stationary phase culture by flow cytometry. We have used flow cytometry to screen for genes that are required to obtain the quiescent cell f ...[more]