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ABSTRACT: Background
Limited information is available regarding long-term effects of air pollution on blood pressure (BP) and hypertension.Objective
We studied whether 1-year exposures to particulate matter (PM) and nitrogen oxides (NOx) were correlated with BP and hypertension in the elderly.Methods
We analyzed cross-sectional data from 27,752 Taipei City residents > 65 years of age who participated in a health examination program in 2009. Land-use regression models were used to estimate participants' 1-year exposures to particulate matter with aerodynamic diameter ? 10 ?m (PM10), coarse particles (PM2.5-10), fine particles (? 2.5 ?m; PM2.5), PM2.5 absorbance, NOx, and nitrogen dioxide (NO2). Generalized linear regressions and logistic regressions were used to examine the association between air pollution and BP and hypertension, respectively.Results
Diastolic BP was associated with 1-year exposures to air pollution, with estimates of 0.73 [95% confidence interval (CI): 0.44, 1.03], 0.46 (95% CI: 0.30, 0.63), 0.62 (95% CI: 0.24, 0.99), 0.34 (95% CI: 0.19, 0.50), and 0.65 (95% CI: 0.44, 0.85) mmHg for PM10 (10 ?g/m3), PM2.5-10 (5 ?g/m3), PM2.5 absorbance (10-5/m), NOx (20 ?g/m3), and NO2 (10 ?g/m3), respectively. PM2.5 was not associated with diastolic BP, and none of the air pollutants was associated with systolic BP. Associations of diastolic BP with PM10 and PM2.5 absorbance were stronger among participants with hypertension, diabetes, or a body mass index ? 25 kg/m2 than among participants without these conditions. One-year air pollution exposures were not associated with hypertension.Conclusions
One-year exposures to PM10, PM2.5-10, PM2.5 absorbance, and NOx were associated with higher diastolic BP in elderly residents of Taipei.
SUBMITTER: Chen SY
PROVIDER: S-EPMC4529013 | biostudies-literature | 2015 Aug
REPOSITORIES: biostudies-literature
Chen Szu-Ying SY Wu Chang-Fu CF Lee Jui-Huan JH Hoffmann Barbara B Peters Annette A Brunekreef Bert B Chu Da-Chen DC Chan Chang-Chuan CC
Environmental health perspectives 20150320 8
<h4>Background</h4>Limited information is available regarding long-term effects of air pollution on blood pressure (BP) and hypertension.<h4>Objective</h4>We studied whether 1-year exposures to particulate matter (PM) and nitrogen oxides (NOx) were correlated with BP and hypertension in the elderly.<h4>Methods</h4>We analyzed cross-sectional data from 27,752 Taipei City residents > 65 years of age who participated in a health examination program in 2009. Land-use regression models were used to e ...[more]