Ontology highlight
ABSTRACT:
SUBMITTER: Wu H
PROVIDER: S-EPMC4529066 | biostudies-literature | 2015 Jul
REPOSITORIES: biostudies-literature
Angewandte Chemie (International ed. in English) 20150601 29
An enantioselective alkoxylation/Claisen rearrangement reaction was achieved by a strategic desymmetrization of 1,4-dienes under the catalysis of (S)-DTBM-Segphos(AuCl)2/AgBF4. This reaction system was highly selective for the formation of 3,3-rearrangement products, providing cycloheptenes with various substitutions in good yield and good to excellent enantioselectivity. This transformation was further extended to bicyclic ring substrates, providing the opportunity to easily assemble 5,6- and 6 ...[more]