Ontology highlight
ABSTRACT:
SUBMITTER: Weigert O
PROVIDER: S-EPMC4530787 | biostudies-literature | 2012 Jan
REPOSITORIES: biostudies-literature
Weigert Oliver O Kopp Nadja N Lane Andrew A AA Yoda Akinori A Dahlberg Suzanne E SE Neuberg Donna D Bahar Anita Y AY Chapuy Bjoern B Kutok Jeffery L JL Longtine Janina A JA Kuo Frank C FC Haley Terry T Salois Maura M Sullivan Timothy J TJ Fisher David C DC Fox Edward A EA Rodig Scott J SJ Antin Joseph H JH Weinstock David M DM
Cancer discovery 20111212 1
<h4>Unlabelled</h4>The relative timing of genetic alterations that contribute to follicular lymphoma remains unknown. We analyzed a donor-recipient pair who both developed grade 2/3A follicular lymphoma 7 years after allogeneic transplantation and donor lymphocyte infusions. Both patients harbored identical BCL2/IGH rearrangements also present in 1 in 2,000 cells in the donor lymphocyte infusion, and the same V(D)J rearrangement, which underwent somatic hypermutation both before and after clonal ...[more]