Ontology highlight
ABSTRACT:
SUBMITTER: Romick-Rosendale LE
PROVIDER: S-EPMC4532301 | biostudies-literature | 2014 Feb
REPOSITORIES: biostudies-literature
Romick-Rosendale Lindsey E LE Legomarcino Anne A Patel Neil B NB Morrow Ardythe L AL Kennedy Michael A MA
Metabolomics : Official journal of the Metabolomic Society 20140201 1
Metabolic profiling of urine and fecal extracts, histological investigation of intestinal ilea, and fecal metagenomics analyses were used to investigate effects of prolonged antibiotic use in mice. The study provides insight into the effects of extended empiric antibiotic therapy in humans. Mice were administered a broad-spectrum antibiotic for four consecutive days followed by oral gavage with <i>Clostridium butyricum</i>, an opportunistic gram-positive pathogenic bacteria commonly isolated in ...[more]