Ontology highlight
ABSTRACT:
SUBMITTER: Han J
PROVIDER: S-EPMC4533315 | biostudies-literature | 2015 Aug
REPOSITORIES: biostudies-literature
Han Junwei J Shi Xinrui X Zhang Yunpeng Y Xu Yanjun Y Jiang Ying Y Zhang Chunlong C Feng Li L Yang Haixiu H Shang Desi D Sun Zeguo Z Su Fei F Li Chunquan C Li Xia X
Scientific reports 20150812
Pathway analyses are playing an increasingly important role in understanding biological mechanism, cellular function and disease states. Current pathway-identification methods generally focus on only the changes of gene expression levels; however, the biological relationships among genes are also the fundamental components of pathways, and the dysregulated relationships may also alter the pathway activities. We propose a powerful computational method, Edge Set Enrichment Analysis (ESEA), for the ...[more]